Youth, Middle Age, Analysis of Clinical Characteristics of Elderly ...

Abstract

Objective: Rectal cancer is the most common malignant tumor, accounting for 60% -80 %Colorectal, accounting for the second digestive tract cancer. With the improvement of living standards, the incidence of disease was increasing. Cancer has become the major diseases threatening human health. And colorectal cancer age of onset are more and more younger age trend. Judging from the age of onset of my cancer, rectal cancer 10 years earlier than gastric cancer, colorectal cancer incidence 30 years of age should be a reminder to age, after 40 years of age, high risk. In recent years, the incidence rate of colorectal cancer actually was an increasing tendency among young people. Different clinical features of colorectal cancer age of great practical significance, Such are the characteristics of different age groups will focus on the treatment of colorectal cancer varies in different age groups to understand the clinical features of rectal cancer will be cancer patients to improve clinical doctors to choose the best treatment options to improve cancer of different ages understanding of the clinical characteristics of patients to achieve for young, middle-aged and elderly patients with rectal cancer early diagnosis and effective treatment purposes?Methods: Retrospective analysis of the Sino-Japanese Friendship Hospital, Jilin University, General Surgery from January 2005 to August 2009 were treated surgically, and pathological diagnosis of 157 cases of primary rectal cancer cases, the thesis according to the World Health Organization on the age division of age?44 years old, 45 to 59 years,?60 years of age were divided into young, middle-aged and elderly group 3.According to different age groups on admission of the chief complaints, analysis of major clinical manifestations (mucus or pus and blood it is hoped, bowel habits, abdominal pain), and treatment time; combination of digital rectal examination, colonoscopy, surgery analysis of different age groups seen in the tumor site ; tumor stage according to Duke?s stage (A period of tumor invasion depth limited to the rectum, the non piercing the deep muscular layer, and no lymph node metastasis; B phase cancer violation of serous membrane layer, can be invasive serous or parenteral outside the surrounding tissue, but still capable of en bloc resection, no lymph node metastasis; C phase cancer violations or violations of full-thickness intestinal wall of full-thickness, but with lymph node metastasis; D period of cancer with distant metastasis, local invasion or lymph node was wide widespread metastasis can not be radical resection). SPSS14.0 statistical package used for data Statistically, the time of admission of different age groups the main clinical manifestations, treatment time, tumor location, pathological type, tumor stage using X2 test, test standard?= 0.05?Results: Rectal cancer in different age groups the main clinical manifestations on admission was no significant (X2 = 3.133, P>0.05); cancer patients of different age groups visiting time there was no significant (X2 = 3.943, P>0.05); different age groups and the rectum cancer tumor from the anal margin of the length there was no significant (X2 = 0.099, P>0.05); different age groups and colorectal cancer tumor histological types, young group and the older group was statistically significant (X2 = 4.771, P 0.05), middle-aged group and the older group was not statistically significant (X2 = 1.95, P>0.05); different age groups rectal tumor staging was no significant (X2 = 0.386, P>0.05)?Conclusion:1?Different age stages of clinical manifestations of patients with rectal cancer was no significant difference?2?Different age stages of cancer treatment in patients with no significant difference in the time?3?Colorectal cancer patients of different ages from the anal margin of the tumor was no significant difference in length?4?Young patients with colorectal cancer than older patients with pathological type of highly malignant pathology, youth group and no significant difference between middle-aged, middle-aged group and no significant difference between the older group?5?Different age stages of rectal tumor staging in patients with no significant difference?

Source: http://www.res-medical.com/oncology/61032

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